Enzyme Mixtures and Complex Biosynthesis
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Edited By:Sanjoy K. BhattacharyaBascom Palmer Eye Institute, University of Miami ISBN: 978-1-58706-216-2 Published: 2007-10-29 This book may be purchased as an eBook (pdf) for $99, or individual chapters (pdf) may be purchased from the list below for $19. |
In this book, an ensemble of examples is provided to illustrate the diversity of approaches and applications to which the multi-enzyme catalysis is currently applied. Enzymes act in living beings as extremely complex, network mixtures that are supportive of all the biochemical transformations on which the life is based. In the biotechnological context, many of the enzymatic processes performed in vitro at both small and industrial scales lie on the enzymatic transformation of a single molecular species for the generation of a product and as catalyzed by a single enzyme. However, the number of technological applications for which cell-free enzyme mixtures are required is increasing and the science of how to combine individual reactions in complex processes is under speedy development. Obviously, any of the current in-progress multi-enzyme processes is fully mimicking the complexity of a living cell or cell community. However, the refined combination of selected enzymes and substrates is offering a new technological approach that is supporting the development of new or improved products in many fields such as food, leather and pharmaceutical industries. This book is unique and presents selective examples of each of these processes have been incorporated in this book by experts in their respective areas.
Chapters available from this book
Enzyme Applications in Leather Processing: Current Scenario and Future Outlook
Palanisamy Thanikaivelan, Jonnalagadda Raghava Rao, Balachandran Unni Nair and Thirumalachari Ramasami
Global leather industry is undergoing paradigm shift from chemical to bio‑based leather making to meet the growing environmental challenges. A short appraisal on the use of enzymes in current leather processing has been presented. Although enzymes find use in many areas of leather processing, ...
Enzyme Catalysis in Fine Chemical and Pharmaceutical Industries
Ganapati D. Yadav, Ashwini D. Sajgure and Shrikant B. Dhoot
Biotechnology is being increasingly adopted by several chemical companies to improve manufacturing sustainability and profitability as regards energy consumption and feed stock access as well as the production of high-value chemicals.1,2 Industrial biotranformations generally center around natural c...
Food Manufacture
Katalin Belafi-Bako
A summary on the role and functions of enzymes and enzyme mixtures in food processing technologies (dairy and meat industry, fish processing, baking, starch and sugar industry, production of beverages and fruit juices, and fat and oil processing), in biosynthesis of food additives (surfactants, flav...
Introduction to Use of Complex Enzyme Mixtures
Sanjoy K. Bhattacharya
Biocatalysts produce substances that are often advantageous compared to traditional methods. They also help synthesize new compounds. To achieve increased or novel production, mutant organisms, tailored enzymes as well as novel combinations of enzymes in reactors are being used and the sphere applic...
Degradation of Keratin and Collagen Containing Wastes by Enzyme Mixtures Produced by Newly Isolated Thermophylic Actinomycetes
Diana Braikova, Evgenia Vasileva-Tonkova, Adriana Gushterova and Peter Nedkov
Thermophilic actinomycetes isolated from Bulgarian and Antarctic soils were investigated for production of collagenolytic and keratinolytic enzymes during growth on keratin- and collagen‑containing wastes used as a sole carbon source. Strains Microbispora sp. A‑35 and Thermoactinomyces s...
Production of Enantiomerically Pure Pharmaceutical Compounds Using Biocatalyst
Ulku MEHMETOĞLU, Emine Bayraktar and Çi𑿞m Babaarslan
The production of single enantiomers of chiral intermediates has become increasingly important especially in pharmaceutical industry. The number of the drugs in single enantiomer form is growing annually. While one of the enantiomers has a desired activity, other has toxic effect or no activity. Dur...
Pharmacogenetic Studies in the Brazilian Population
G. Suarez-Kurtz and S.D.J. Pena
By virtue of being the product of the genetic admixture of three ancestral roots: Europeans, Africans and Amerindians, the Brazilian population displays very high levels of genomic diversity and several peculiarities in its genetic structure that are reviewed in this chapter. After painting t...
New Technologies in the Production of Food Enzymes
Maria Papagianni
Organisms evolve enzyme systems determined to function optimally in their natural environment for survival purposes. However, the optimal enzyme system for chemical or food processes may require characteristics that might differ considerably from those found in nature. Therefore, the greatest opport...
Metabolic Engineering in the Targeted Improvement of Cellular Properties in Plants vis-à-vis Biopharmaceutical Production
Ramkrishna Sen
Modern biotechnology has now evolved from the phase of genetic engineering for introducing single gene traits to the phase of metabolic engineering for manipulating multigenic traits, thereby coding for complete metabolic pathways, bacterial operons or therapeutic molecules that require an assembly ...
Utilization of Enzymes and Enzyme Mixtures in Abatement of Carbon Dioxide Pollution at Source
Mabel Algeciras and Sanjoy K. Bhattacharya
Carbon dioxide is a major gaseous pollutant released as a result of burning carbonaceous material and has been implicated in global warming. The utilization of enzyme mixtures for continuous fixation of carbon dioxide from emission sources has been reviewed. Two novel approaches have been recently d...
