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Branching Morphogenesis


Edited By:

Jamie A. Davies
Edinburgh University
College of Medicine

ISBN: 978-0-387-25615-3
Published: 2005-10-15

This book may be purchased as an eBook (pdf) for $99, or individual chapters (pdf) may be purchased from the list below for $19.





Chapters available from this book


Branching Morphogenesis of the Prostate

A.A. Thomson and P.C. Marker

The prostate is a male sex accessory organ whose development is regulated by androgens and mesenchymal/epithelial interactions. The organ comprises branched epithelial ducts within a stroma consisting of fibroblasts and smooth muscle as well as other components such as vasculature and nerves. Th...

Branching Morphogenesis in Vertebrate Neurons

Katherine M. Kollins and Roger W. Davenport

Within the developing vertebrate nervous system, strict control of branching morphogenesis is essential for establishing appropriate circuitry, since the geometry of neuronal arbors critically influences their functional properties. Thus, identification of the specific molecules and mechanisms in...

How Is the Branching of Animal Blood Vessels Implemented?

Sybill Patan

The Blood Circulatory System: Tree Analogy Versus Network: For centuries, the cardiovascular system of animals has been described as a branching tree with the heart in its very centre.1 Although this description dates back to Galen1 (c. 130-200 A.D.) and structural similarities with trees are obv...

Extracellular Matrix Remodeling in Breast Branching Morphogenesis and Breast Cancer: The Double-Edged Sword

Eva A Turley and Mina J Bissell

That differentiation and malignancy are different faces of the same coin is now almost a clich?.1-4 Although widely accepted as fact, exactly what are the points of similarity and differences that contribute to normal morphogenesis on the one hand and to neoplastic progression on the other? How c...

Why a Book on Branching, and Why Now?

Jamie A. Davies

In a world overloaded with information, in which university library shelves bend under the weight of worthy tomes and the number of journals has been doubling every fifteen years,1,2 a prospective reader is fully entitled to eye any new text suspiciously and to ask whether there is really a need ...

Afterword

Jamie Davies

The subject of this book - branching morphogenesis - may seem to be very narrow, yet its chapters extend into a surprising number of aspects of modern biological science. The systems examined range from genes and signal transduction pathways, through morphogenetic apparatus within single cells to...

Uterine Glands

Thomas E. Spencer, Karen D. Carpenter, Kanako Hayashi and Jianbo Hu

This chapter focuses on the comparative development and mechanisms regulating branch ing morphogenesis of endometrial glands in the mammalian uterus. All uteri contain endometrial glands that secrete substances, termed histotroph, essential for conceptus (embryo/fetus and associated extraembryoni...

Physical Mechanisms of Branching Morphogenesis in Animals: From Viscous Fingering to Cartilage Rings

Vincent Fleury, Tomoko Watanabe, Thi-Hahn Nguyen, Mathieu Unbekandt, David Warburton, Marcus Dejmek, Minh Binh, Nguyen, Anke Lindner and Laurent Schwartz

From a physicist’s point of view, and regardless of the genetic controls, the branching mechanisms of many organs and glands look similar. Most generally, an epithelium forms a pouch-like sheet which elongates and branches repeatedly. During the final steps of organogenesis, the mesenchyme is vas...

Branching Morphogenesis in Mammalian Kidneys

Jamie A. Davies

Branching morphogenesis is an important mechanism for the development of the permanent kidneys of reptiles, mammals and birds. Branching of renal epithelia is similar to that seen in the other organs described in this book1 but organogenesis of kidneys has unique features that, at the expense of ...

Branching in Colonial Hydroids

I.A. Kosevich

Cnidarians are primitive multi-cellular animals whose body is constructed of two epi thelial layers and whose gastric cavity has only one opening. Most cnidarians are colo nial. Colonial hydroids with their branched body can be regarded as a model for the whole phylum and are the most- studied cn...

Branching in Fungal Hyphae and Fungal Tissues: Growing Mycelia in a Desktop Computer

David Moore, Liam J. McNulty and Audrius Meskauskas

In mycelial fungi the formation of hyphal branches is the only way in which the number of growing points can be increased. Cross walls always form at right angles to the long axis of a hypha, and nuclear division is not necessarily linked to cell division. Consequently, no matter how many nuclear...

Branching of Single Cells in Arabidopsis

Daniel Bouyer and Martin Huelskamp

Branching of single cells is controlled by intracellular or extracellular cues that lead to the establishment of a polarity axis and subsequently to the local activation of growth activ ity. Three model cell types in Arabidopsis, that elucidate different mechanisms of branch formation in single c...

Embryonic Salivary Gland Branching Morphogenesis

Tina Jaskoll and Michael Melnick

Salivary submandibular gland (SMG) morphogenesis is regulated by the functional integration of stage-specific growth factor- , cytokine- and transcription factor-mediated signaling which mediates specific patterns of cell proliferation, cell quiescence, apoptosis, and histodifferentiation. We des...


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