Nanomedicine, Volume IIA: Biocompatibility
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Edited By:Robert A. Freitas Jr.Zyvex Corp. Richardson, Texas ISBN: 978-1-57059-700-8 Published: 2003-09-26 This book may be purchased as an eBook (pdf) for $79, or individual chapters (pdf) may be purchased from the list below for $19. |
Nanomedicine, Volume IIA: Biocompatibility
The safety, effectiveness, and utility of medical nanorobotic devices will critically depend upon their biocompatibility with human organs, tissues, cells, and biochemical systems. In this Volume, we broaden the definition of nanomedical biocompatibility to include all of the mechanical, physiological, immunological, cytological, and biochemical responses of the human body to the introduction of artificial medical nanodevices, whether “particulate” (large doses of independent micron-sized individual nanorobots) or “bulk” (nanorobotic organs assembled either as solid objects or built up from trillions of smaller artificial cells or docked nanorobots inside the body) in form.Chapters available from this book
Nanorobot Mechanocompatibility
Robert A. Freitas
Unlike pharmaceutical agents whose interactions with biology are largely chemical in nature, medical nanorobots will interact both chemically and mechanically (Chapter 15.1) with human tissues and cells. Similarly, traditional biomedical device implants (Section 15.2.1) produce both chemical and...
Systemic Nanorobot Distribution and Phagocytosis
Robert A. Freitas
Traditional biocompatibility focuses on the implant-host interface. But a human patient is an interconnected structure with various mechanisms permitting physical exchange among all of its tissues and organs. Of particular interest in nanomedicine is the movement of solid bodies and particulate ...
Biocompatibility of Nanomedical Materials
Robert A. Freitas
A great deal is already known about the biocompatibility of various materials that are likely to find extensive use in medical nanorobots. Chapter 15.3 includes a review of the experimentally-determined overall biocompatibility of diamond (Section 15.3.1), carbon fullerenes (Section 15.3.2), non...
Classical Biocompatibility
Robert A. Freitas
The question of biocompatibility234-237 arises whenever any foreign substance — be it natural materials,6054 therapeutic cells, a transplanted organ, an artificial implant, or a medical nanorobot — is placed inside the human body for medical purposes. The most general definition of biocompatibil...
Are Diamondoid Nanorobots Hazardous?
Robert A. Freitas
I diamondoid substances (Chapters 2 and 11). The first and most obvious question regarding biocompatibility thus must be: What health risks, if any, are associated with the in vivo use of diamondoid devices or their detached parts, components, or detritus? There may be billions or trillions of n...
Preface
Robert A. Freitas
“Compatibility” most broadly refers to the suitability of two distinct systems or classes of things to be mixed or taken together without unfavorable results.2004 More specifically, the safety, effectiveness, and utility of medical nanorobotic devices will critically depend upon their biocompati...
