Selective Serotonin Reuptake Inhibitors (SSRIs): Past Present and Future
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Edited By:S. Clare StanfordUniversity College - London ISBN: 978-1-57059-649-0 Published: 1999-12-01 |
The SSRIs have had a major impact on the treatment of depression and one, Prozac, has even attained cult status. Yet, their predecessors are still used with impunity and we have no definitive explanation for their therapeutic effects. In reviewing the established and novel indications for treatment with these drugs, SSRIs: Past, Present and Future, incorporates a frank and detailed appraisal of their safety, efficacy and tolerability as well as exploring their underlying neurobiology.
Chapters available from this book
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The introduction of the selective serotonin reuptake inhibitors (SSRIs) into medical treatment in the 1980s revolutionized psychiatric practice and fueled the interest in the role of serotonin (5-hydroxytryptamine, 5-HT) in the underlying neurobiology of the psychiatric disorders. In ...
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The discovery in the 1950s that imipramine and iproniazid had antidepressant properties was soon followed by the recognition that they acted on monoamine systems. This laid the foundation for two interrelated but logically distinct theories which have dominated biological research int...
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The selective serotonin reuptake inhibitors (SSRIs) have increased in popularity and extent of use since their introduction. At the same time, our knowledge concerning the relationship between suicide and depression has increased. The impact of this group of drugs on this knowledge has b...
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