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Synthetic Polymers for Biotechnology and Medicine


Edited By:

Ruth Freitag
Ecole Polytechnique Fédérale de Lausanne

ISBN: 978-1-58706-027-4
Published: 2002-12-01




Chapters available from this book


Membrane Adsorbers for Decontamination and Leukocyte Removal

Galya Tishchenko and Miroslav Bleha

Membranes were originally developed as agents (filters, sieves) for solid-liquid separations by mechanical means. In this context any interaction (adsorption) of the components with the membrane material was to be avoided. Recently however, the controlled (selective) adsorption of cer...

Molecularly Imprinted Polymers: A New Dimension in Analytical Bioseparation

Oliver Brüggemann

Biological interactions, for example the interaction between an antibody and its antigen or between an enzyme and its substrate, are in most cases closely linked to the three–dimensional structure of the protein. Antibodies as well as enzymes are large (protein) molecules made up...

Stimulus Responsive Surfaces: Possible Implications for Biochromatography,

Igor Yu Galaev, Bo Mattiasson

Functional polymers, which can react, adjust or modulate their physicochemical character, i.e., in most cases their water–solubility, in response to an external stimulus, are generally referred to as "smart materials" or, if they are water–swellable, as "intelligent gels" or...

Synthetic Displacers for Preparative Biochromatography

Ruth Freitag and Christine Wandrey

Biotechnology has become an important industry with a major impact on the economic development in the highly industrialized countries. Bioproduction has the reputation of being "clean" and environmentally friendly, an advantage which is in part paid for by complex production environme...

Affinity Precipitation: Stimulus–Responsive Polymers for Bioseparation

Ruth Freitag

The modern biotechnology industry has provided the medical community with a new type of pharmaceutical, namely recombinant proteins and peptides. The number of such protein–based drugs is already impressive and expected to increase considerably in the future, as the function and ...

Synthetic and Semisynthetic Polymers as Vehicles for In Vitro Gene

Martin Jordan

The impact of molecular biology on everyday life has increased enormously over the last two decades. Medical, pharmaceutical and lately even agricultural applications of "gene technology" have become standard, if sometimes controversially viewed procedures. The feasibility of this "revol...

Cell Encapsulation:Generalities, Methods, Applications and Bioartificial Pancreas Case Study

Gabriela Grigorescu and David Hunkeler

One of the most powerful group of chemicals in the body are organic compounds collectively referred to as hormones. The glands responsible for the production and release of hormones comprise the endocrine system. Endocrine activities have been identified in certain organs, such as the heart, kidn...


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