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Transplantation of Neural Tissue into the Spinal Cord, Second Edition


Edited By:

Antal Nogradi
University of Szeged
Albert Szent-Györgyi Medical Center
Szeged, Hungary

ISBN: 978-0-387-26355-7
Published: 2005-12-15

This book may be purchased as an eBook (pdf) for $99, or individual chapters (pdf) may be purchased from the list below for $19.





Chapters available from this book


Replacement of Specific Populations of Cells: Glial Cell Transplantation into the Spinal Cord

Antal Nogradi

In recent years an increasing number of results of successful spinal cord transplantation has been reported. Apart from theoretical interest the main aim of these experiments was to find a possible way to improve the consequences of spinal cord injury or neurological disorders affecting the spina...

Encouraging Regeneration of Host Neurones: The Use of Peripheral Nerve Bridges, Glial Cells or Biomaterials

Antal Nogradi

Recent results challenged the dogma that regeneration of CNS axons is impossible. These findings stimulated the interest of experimental neurobiologists and led to research that improved our understanding of the rules that control regeneration of structures in the mammalian spinal cord after inju...

Replacement of Specific Neuronal Populations in the Spinal Cord

Antal Nogradi

As discussed in Chapter 5, embryonic spinal cord grafted into the injured spinal cord of neonatal and adult animals can serve as a relay tissue bridge for axonal growth and regeneration, and promote some degree of functional recovery in the host. In these experiments the pattern of host axonal pr...

Anatomy and Physiology of the Spinal Cord

Antal Nogradi amd Gerta Vrbovi

The spinal cord is part of the central nervous system (CNS), which extends caudally and is protected by the bony structures of the vertebral column. It is covered by the three membranes of the CNS, i.e., the dura mater, arachnoid and the innermost pia mater. In most adult mammals it occupies only...

Recovery of Function After Spinal Cord Injury

Gavin Clowry and Urszula Slawinska

Injuries to the spinal cord can produce variable deficits in movement, sensation and auto nomic function. In humans and other primates sudden transection of the cord results initially in a state known as “spinal shock” in which there is complete loss of sensation, in the ability to evoke voluntar...

Recovery of Lost Spinal Cord Function by Facilitating the Spinal Cord Circuits Below the Lesion

Urszula Slawinska

In the previous Chapter strategies that effort to restore the lost function after spinal cord injury a) by attempting to reconnect anatomically the separated parts of the spinal cord by encouraging regeneration of axons across the damaged parts of the spinal cord; b) by providing grafts that woul...

Encouraging Regeneration of Host Neurones: Transplantation of Neural Tissues into the Injured Spinal Cord Grafts of Embryonic Neural Tissue

Gerta Vrbová

Traumatic injury to the spinal cord causes disruption of the long descending and ascend- ing pathways, degeneration of neurones in the lesioned area and destruction of the intrinsic spinal connections. The natural history of spinal cord injury involves formation of a dense gliotic scar surround...

Encouraging Regeneration of Host Neurones: The Use of Peripheral Nerve Bridges, Glial Cells or Biomaterials

Antal Nógrádi

Recent results challenged the dogma that regeneration of CNS axons is impossible. These findings stimulated the interest of experimental neurobiologists and led to re- search that improved our understanding of the rules that control regeneration of structures in the mammalian spinal cord after ...


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