Selective Sweep
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Edited By:Dmitry NurminskyTufts University ISBN: 978-0-306-48235-9 Published: 2005-01-26 This book may be purchased as an eBook (pdf) for $99, or individual chapters (pdf) may be purchased from the list below for $19. |
Chapters available from this book
Rapid Evolution of Sex-related Genes: Sexual Conflict or Sex-specific Adaptations?
Alberto Civetta and Rama S. Singh
A number of recent studies have suggested that the rapid evolution of genes involved in sexual reproduction is driven by conflict between the sexes. Such genes include the ones that have a role in mating behavior, postmating gamete interactions, and fertilization (i.e., sex-related genes). Howeve...
Distribution and Abundance of Polymorphism in the Malaria Genome
Stephen M. Rich
Plasmodium falciparum is the most deadly of the four human malaria parasites, causing as many as 500 million malaria cases per year and more than 2 million deaths.1 Despite more than a century of biomedical research and unprecedented (indeed, unsurpassed) measures of international collaboration t...
Selective Sweeps in Structured Populations-empirical Evidence and Theoretical Studies
Thomas Wiehe, Karl Schmid, Wolfgang Stephan
Properties of most selection models have been explored for panmictic populations, but little work has been done for substructured populations. In a substructured population, background selection against deleterious mutations has been shown to increase FST, a relative measure of differentiation be...
Detecting Hitchhiking from Patterns of DNA Polymorphism
Justin C. Fay and Chung-I Wu
The genetic basis of adaptive evolution has long escaped the grasp of evolutionary geneticists due to the difficulty of mapping an organism’s phenotype to its genotype. However, adaptive substitutions may also be identified by their effects on linked neutral variation. This has made it possible t...
Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila
Rob J. Kulathinal, Stanley A. Sawyer, Carlos D. Bustamante, Dmitry I. Nurminsky, Rita Ponce, Jos? M. Ranz and Daniel L. Hartl
The Sdic gene cluster at the base of the X-chromosome is unique to the lineage of Drosophila melanogaster. The repeating unit in the cluster was formed from a duplication and fusion of the genes, AnnX and Cdic, which juxtaposed the 3' untranslated region of AnnX to the third intron of Cdic. AnnX ...
Inferring Evolutionary History through Interand Intraspecific DNA Sequence Comparison The Drosophila janus and ocnus Genes
John Parsch, Colin D. Meiklejohn and Daniel L. Hartl
Statistical analysis of aligned DNA sequences, both among and within species, has proven to be a valuable tool for inferring the evolutionary history of genetic loci. Of particular interest are cases where the observed data depart from the neutral expectation and suggest adaptive evolution due to...
Periodic Selection and Ecological Diversity in Bacteria
Frederick M. Cohan
Biodiversity in the bacterial world is strongly influenced by “periodic selection,” in which natural selection recurrently purges diversity within a bacterial population. Owing to the extreme rarity of recombination in bacteria, selection favoring an adaptive mutation eliminates nearly all the di...
A Novel Test Statistic for the Identification of Local Selective Sweeps Based on Microsatellite Gene Diversity
Christian Schlotterer and Daniel Dieringer
Genome wide population surveys have recently been established as a promising approach for the identification of genomic regions subject to directional selection. Nevertheless, the analysis of multiple markers requires novel approaches for the identification of selection. In this report we introdu...
