Chapter category: Vaccines
Immunobiology of HPV Infection
Vaccines for Human Papilloviruses Infection and Anogenital Disease
Edited by: Robert W. TindleISBN: 1-57059-589-5
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Chapter authors:
Graham R. Leggatt and Ian H. Frazer
T of epithelial cells. An understanding of the viral life cycle, models of infection and the host immune response is an essential first step in the development of therapeutic or prophylactic vaccines. The literature suggests that strategies to elicit neutralizing anti-capsid protein antibodies will be useful in prophylactic vaccines for HPV, while generation of CTL specific for E6/E7 may be more useful for therapeutic vaccines. Targeting of the immune system to the infected epithelium and provision of an immunostimulatory environment will also be important.
Additional chapters from this book:
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Graham R. Leggatt and Ian H. Frazer
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