Chapter category: Nanomedicine
Classical Biocompatibility
Nanomedicine, Volume IIA: Biocompatibility
Edited by: Robert A. Freitas Jr.ISBN: 1-57059-700-6
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Chapter authors:
Robert A. Freitas
The question of biocompatibility234-237 arises whenever any foreign substance — be it natural materials,6054 therapeutic cells, a transplanted organ, an artificial implant, or a medical nanorobot — is placed inside the human body for medical purposes. The most general definition of biocompatibility is: “the ability of a material to perform with an appropriate host response in a specific application”,230 or, alternatively: “the exploitation by materials of the proteins and cells of the body to meet a specific performance goal”,231 but neither of these really tells the whole story. The term “biocompatibility,” as used in this book, will refer to an assessment of the totality of nanorobot surface material-tissue interactions, both local and systemic. These interactions classically may include:231-234
Additional chapters from this book:
Nanorobot Mechanocompatibility
Robert A. Freitas
Unlike pharmaceutical agents whose interactions with biology are largely chemical in nature, medical nanorobots will interact both chemically and mechanically (Chapter 15.1) with human tissues and ...
Systemic Nanorobot Distribution and Phagocytosis
Robert A. Freitas
Traditional biocompatibility focuses on the implant-host interface. But a human patient is an interconnected structure with various mechanisms permitting physical exchange among all of its tissues ...
Biocompatibility of Nanomedical Materials
Robert A. Freitas
A great deal is already known about the biocompatibility of various materials that are likely to find extensive use in medical nanorobots. Chapter 15.3 includes a review of the experimentally-deter...
Classical Biocompatibility
Robert A. Freitas
The question of biocompatibility234-237 arises whenever any foreign substance — be it natural materials,6054 therapeutic cells, a transplanted organ, an artificial implant, or a medical nanorobot —...
Are Diamondoid Nanorobots Hazardous?
Robert A. Freitas
I diamondoid substances (Chapters 2 and 11). The first and most obvious question regarding biocompatibility thus must be: What health risks, if any, are associated with the in vivo use of diamondoid...
Preface
Robert A. Freitas
“Compatibility” most broadly refers to the suitability of two distinct systems or classes of things to be mixed or taken together without unfavorable results.2004 More specifically, the safety, eff...

