Chapter category: Heart
Adrenergic Stress
The Etiopathogenesis of Coronary Heart Disease:
A Heretical Theory Based on Morphology
Second Edition
Edited by: Giorgio Baroldi and Malcolm D. SilverISBN: 1-58706-076-0
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Chapter authors:
Baroldi, Giorgio, Malcolm Silver
For millenia mors subita (sudden death) was more a voodoo-religious concept bio-pathologic problem. Cases are reported episodically in ancient writings Phidippides, cited above, who died suddenly crying to the Athenians “Nike” against the Persian, having run 22 mi. 1,470 yd from Marathon to Athens. association between sudden death and heart disease came with Lancisi’s publication the first scientific report based on autopsy findings. Subsequently, sudden death recognized as part of ischemic heart disease. Do similarities exist between the 18th Century and modern societies? At best, relationships seem tenuous. Modern societies are populous, and technologically advanced while Rome in 1700 was at a peak of decadence and had a small, technologically unsophisticated population. A possible common denominator the two, apparently opposite, social patterns might be mental depression consequent hope. Yet, both societies, faced tension, stresses and depression. Eliot (1994) reported epidemic of sudden death amongst National Aeronautics and Space Administration when, in 1968 that agency faced budget cuts with the loss of highly technical jobs available in other industries. This caused environmental instability. Other similar were reported to show the relationship between depression and socio-economic factors et al, 2000). In the meantime, atherosclerosis, per se, is an old human disease being Egyptian mummies of high social class (Ruffer, 1911). However, the deluge of coronary disease cases started only when society became affluent in a highly unstable economic technologic enviroment characterized by many stimuli and related tensions.
Additional chapters from this book:
Tables and References for the Etiopathogenesis of Coronary Heart Disease
Baroldi, Giorgio, Malcolm Silver
Complete tables and references for the Etiopathogenesis of Coronary Heart Disease.
ILLUSTRATIONS for the Etiopathogenesis of Coronary Heart Disease
Baroldi, Giorgio, Malcolm Silver
Complete Illustrations for this book.
Adrenergic Stress
Baroldi, Giorgio, Malcolm Silver
For millenia mors subita (sudden death) was more a voodoo-religious concept bio-pathologic problem. Cases are reported episodically in ancient writings Phidippides, cited above, who died suddenly cr...
Revisiting Dogma Related to Coronary Artery Disease
Baroldi, Giorgio, Malcolm Silver
Science evolves as a continuous turnover of hypotheses that require constant review/ revision. It is time to reconsider each single caryatid which sustains the present conceptual temple dealing with...
Findings in Acute Coronary Syndromes
Giorgio Baroldi, Malcolm Silver
In keeping with the “unifying theory”, presented by Gorlin et al 1986, CHD has a common etiopathogenetic denominator, i.e., rupture of an atherosclerotic plaque and consequent thrombosis and/or micr...
Natural History of the Human Coronary Atherosclerotic Plaque and Related Forms of Myocardial Injuries
Giorgio Baroldi, Malcolm Silver
The first need was to reconstruct the natural history of the morphology of the coronary atherosclerotic plaque seen in humans with and without CHD. Since different arterial vessels have dissimilar h...
Comparative Pathologic Study
Giorgio Baroldi, Malcolm Silver
The objectives were first to compare the different morphologic variables in acute and chronic coronary syndromes to establish the morpho-functional significance of the changes found in coronary vess...
Plastic Cast Study of Coronary Vessels
Giorgio Baroldi, Malcolm Silver
Coronary heart disease (CHD) becomes epidemic in any society that transforms itself from an agricultural one to an industrial-technological system with an associated behavioural alteration in the po...

