Chapter category: Neurodegenerative Disease
Neuroprotection by cAMP: Another Brick in the Wall
Brain Repair
Edited by: Mathias BährISBN: 0-306-47859-5
» Get more information about this book at landesbioscience.com «
Chapter authors:
Mariana S. Silveira and Rafael Linden
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Additional chapters from this book:
Transplantation in Parkinson’s Disease: The Future Looks Bright
Gesine Paul, Young Hwan Ahn, Jia-Yi Li and Patrik Brundin
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects almost 1% of the population above the age of 50. Early in the course of the disease, patients primarily di...
The Collagenous Wound Healing Scar in the Injured Central Nervous System Inhibits Axonal Regeneration
Susanne Hermanns, Nicole Klapka, Marcia Gasis and Hans Werner Muller
Following traumatic injuries of the central nervous system (CNS) a wound healing scar, resembling the molecular structure of a basement membrane and mainly composed of Collagen type IV and associate...
Neuroprotection by cAMP: Another Brick in the Wall
Mariana S. Silveira and Rafael Linden
Programmed cell death occurs in the nervous system both in normal development as well as in pathologic conditions, and is a key issue related to both brain repair and neurodegenerative diseases. Mod...
The Role of Ionotropic Purinergic Receptors (P2X) in Mediating Plasticity Responses in the Central Nervous System
F. Florenzano, M.T. Viscomi, F. Cavaliere, C. Volonti, M. Molinari
The past few years have witnessed increasing interest in the field of purinergic signalling and have recognised ATP as an extracellular messenger eliciting a wide array of physi ological effects in ...
The Glial Response to Injury and Its Role in the Inhibition of CNS Repair
James W. Fawcett
The failure of axon regeneration after CNS injury is due to an inadequate or inappropri ate regenerative response from damaged CNS axons, and to a CNS environment that inhibits regeneration. This in...
DSD-1-Proteoglycan/Phosphacan and Receptor Protein Tyrosine Phosphatase-Beta Isoforms During Development and Regeneration of Neural Tissues
Andreas Faissner, Nicolas Heck, Alexandre Dobbertin and Jeremy Garwood
Interactions between neurons and glial cells play important roles in regulating key events of development and regeneration of the CNS. Thus, migrating neurons are partly guided by radial glia to the...
A Kinase with a Vision: Role of ERK in the Synaptic Plasticity of the Visual Cortex
Gian Michele Ratto and Tommaso Pizzorusso
We look at these written words with two eyes, their neuronal representations are elabo rated separately in the two retinae and they are conveyed to two separate zones of the thalamus. The segrega...
Lesion-Induced Axonal Sprouting in the Central Nervous System
Thomas Deller, Carola A. Haas, Thomas M. Freiman, Amie Phinney, Mathias Jucker and Michael Frotscher
Injury or neuronal death often come about as a result of brain disorders. Inasmuch as the damaged nerve cells are interconnected via projections to other regions of the brain, such lesions lead ...
Cell Death in the Nervous System
Kerstin Krieglstein
Programmed cell death is a fundamental and essential process in development and tissue homeostasis of multicellular organisms. About half of all neurons produced during neurogenesis die before t...
Role of Endogenous Neural Stem Cells in Neurological Disease and Brain Repair
Jörg Dietrich and Gerd Kempermann
There is abundant evidence that neural stem cells persist in the adult mammalian brain – including humans – throughout lifetime and support ongoing neurogenesis in re- stricted regions of the...
Attempts to Restore Visual Function After Optic Nerve Damage in Adult Mammals
Tomomitsu Miyoshi, Takuji Kurimoto and Yutaka Fukuda
Retinal ganglion cells (RGCs) and their axons, i.e., optic nerve (ON) fibers, provide a good experimental model for research on damaged CNS neurons and their functional recovery. After the ON tr...
