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Chapter category: Bioinformatics

Limitations and Potential for the Identification of Ecologically Important Genes

Chapter authors:
Christian Schlotterer

A recent series of publications demonstrated that identification of genomic regions subjected to positive selection (hitchhiking mapping) is possible and could be applied in an ecological context. This review focuses on the use of microsatellite markers in genome scans for the identification of beneficial mutations. The pitfalls and potential of the lnR? test statistic are discussed as well as different approaches for the identification of the molecular change(s) underlying an observed selective sweep.

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