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Chapter category: DNA

Schistosome Long Terminal Repeat Retrotransposons

This chapter appears in the following book:

Mobile Genetic Elements in Metazoan Parasites

Edited by: Paul J. Brindley
ISBN: 978-1-58706-093-9
» Get more information about this book at landesbioscience.com «

Chapter authors:
Claudia S. Copeland, Thewarach Laha and Paul J. Brindley*


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The human schistosomes, blood flukes of the Genus Schistosoma, have a large genome estimated to be at least 270 megabase pairs (haploid) in size, arrayed on eight pairs (2n = 16) of chromosomes including the Z (male) and W (female) sex chromosomes. The genome appears to include about 14,000 protein encoding genes and a large amount of repetitive sequences. Much of this repetitive component of the schistosome genome is comprised of mobile genetic elements. Of these elements, an expanding number of discrete long terminal repeat (LTR) retrotransposons have been identified in the past five years. The identity, structure, phylogenetic relationships, and size contributions of these schistosome LTR retrotransposons are reviewed here. These elements include the gypsy-like or Pao/BEL -like retrotransposons Boudicca, Sinbad, fugitive, Saci-1, Saci-2, and Saci-3 from Schistosoma mansoni and Gulliver from Schistosoma japonicum.

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Schistosome Long Terminal Repeat Retrotransposons

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Schistosome Long Terminal Repeat Retrotransposons

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