Chapter category: RNA
Riboswitches As Genetic Control Elements
Nucleic Acid Switches and Sensors
Edited by: Scott K. SilvermanISBN: 0-387-37491-4
» Get more information about this book at landesbioscience.com «
Chapter authors:
Ali Nahvi and Ronald R. Breaker
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Additional chapters from this book:
Allosteric Ribozymes As Molecular Sensors and Genetic Regulatory Switches
Garrett A. Soukup
Since the discovery of RNA catalysts, biotechnology has focused heavily on utilizing ribozymes as reagents to control RNA processing and gene expression. However, ribozymes can also be manipulat...
Ribozymes and Deoxyribozymes Switched by Oligonucleotides
Dipankar Sen and Edward K. Y. Leung
This chapter explores the diverse strategies reported in recent years for using oligonucleotides to switch the catalytic activity of allosteric ribozymes and deoxyribozymes (DNAzymes). The earliest ...
Protein-Switched Ribozymes
Tan Inoue* and Yoshiya Ikawa
Specific RNA-binding proteins regulate RNA conformations in protein-switched ribozymes. Ribozyme activity can be regulated with RNA-binding proteins, as in the case of natural RNP ribozymes like RNa...
Riboswitches As Genetic Control Elements
Ali Nahvi and Ronald R. Breaker
Riboswitches are metabolite-sensing RNA elements that are present in the noncoding portions of certain messenger RNAs. Each riboswitch carries an aptamer that is highly selective for its target meta...
Switchable RNA Motifs As Drug Targets
Eric Westhof, Boris François and Quentin Vicens
RNA molecules are highly negatively charged polymers that form intricate three-dimensional assemblies involving recurrent structural motifs. Therefore, in order to understand the molecular recogniti...
Protein-induced RNA Switches in Nature
Oliver Mayer, Nikolai Windbichler, Herbert Wank and Renée Schroeder
The conformational flexibility of RNA is the basis for its functional versatility. RNA molecules can fold into functionally diverse structures, providing the grounds for great regulatory potential. ...
Fluorescence-Signaling Nucleic Acid-Based Sensors
Razvan Nutiu, Lieven P. Billen and Yingfu Li
It is widely known that two single-stranded nucleic acids with complementary sequences have the inherent ability to form Watson-Crick duplex structures. The simplicity and sequence-specificity of du...
