Chapter category: Reproductive Biology
The Role of the Leydig Cell in Spermatogenic Function
Molecular Mechanisms
in Spermatogenesis
Edited by: C. Yan ChengISBN: 978-0-387-79990-2
» Get more information about this book at landesbioscience.com «
Chapter authors:
Renshan Ge, Guorong Chen and Matthew P. Hardy
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Renshan Ge
The Population Council; and, The Rockefeller University
Guorong Chen
The Population Council; and, The Rockefeller University
Matthew P. Hardy
The Population Council; and, The Rockefeller University
Additional chapters from this book:
Proteases and Their Cognate Inhibitors of the Serine and Metalloprotease Subclasses, in Testicular Physiology
Brigitte Le Magueresse-Battistoni
The testis is a highly dynamic organ not only in the fetal stage but also during postnatal development and in adult life. It is composed of two major compartments: the interstitium with the steroidoge...
The Sertoli Cell Cytoskeleton
A. Wayne Vogl, Kuljeet S. Vaid and Julian A. Guttman
Spermatogenesis is a highly complicated process in which functional spermatozoa (haploid, 1n) are generated from primitive mitotic spermatogonia (diploid, 2n). This process involves the differentiatio...
The Role of the Leydig Cell in Spermatogenic Function
Renshan Ge, Guorong Chen and Matthew P. Hardy
Two anatomically distinct compartments, respectively, the interstitium where Leydig cells reside and the seminiferous tubules contribute the major functions of the testis, testosterone secretion and s...
Blood-Testis Barrier, Junctional and Transport Proteins and Spermatogenesis
Brian P. Setchell
The term “blood-testis barrier” appears to have been first used by Chiquoine in an article on effects of cadmium on the testis, but evidence for such a barrier already existed, dating back to the earl...
Cross-Talk between Tight and Anchoring Junctions—Lesson from the Testis
Helen H.N. Yan, Dolores D. Mruk, Will M. Lee and C. Yan Cheng
Spermatogenesis takes place in the seminiferous tubules in adult testes such as rats, in which developing germ cells must traverse the seminiferous epithelium while spermatogonia (2n, diploid) undergo...
Transcription Regulation in Spermatogenesis
Wing-Yee Lui and C. Yan Cheng
Spermatogenesis is a highly coordinated process in which diploid spermatogonia (2n) differentiate into mature haploid (1n) spermatozoa in the seminiferous epithelium. In this process, spermatogonia un...
Estrogens and Spermatogenesis
Chandrima Shaha
For many years androgens were thought to be the primary hormones required for proper functioning of the male reproductive system, and testes were shown to be the major producers of the hormone. In the...
Nitric Oxide and Cyclic Nucleotides: Their Roles in Junction Dynamics and Spermatogenesis
Nikki P.Y. Lee and C. Yan Cheng
Spermatogenesis is a highly complicated process in which functional spermatozoa (haploid, 1n) are generated from primitive mitotic spermatogonia (diploid, 2n). This process involves the differentiatio...
Inflammatory Networks in the Control of Spermatogenesis: Chronic Inflammation in an Immunologically Privileged Tissue?
Moira K. O′Bryan and Mark P. Hedger
Spermatogenesis is a complex, organized process involving intimate interactions between the developing germ cells and supporting Sertoli cells. The process is also highly regulated. Studies suggest th...
Spermatogenesis and Cycle of the Seminiferous Epithelium
Rex A. Hess and Luiz Renato de Franca
Spermatogenesis is a complex biological process of cellular transformation that produces male haploid germ cells from diploid spermatogonial stem cells. This process has been simplified morphologicall...
Extracellular Matrix and Its Role in Spermatogenesis
Michelle K.Y. Siu and C. Yan Cheng
In adult mammalian testes, such as rats, Sertoli and germ cells at different stages of their development in the seminiferous epithelium are in close contact with the basement membrane, a modified form...
Antioxidant Systems and Oxidative Stress in the Testes
R. John Aitken and Shaun D. Roman
Spermatogenesis is an extremely active replicative process capable of generating approximately 1,000 sperm a second. The high rates of cell division inherent in this process imply correspondingly high...
Selenium, a Key Element in Spermatogenesis and Male Fertility
Carla Boitani and Rossella Puglisi
Selenium is essential for normal spermatogenesis of mammals and its critical role is mainly mediated by two selenoproteins, namely phospholipid hydroperoxide glutathione peroxidase (PHGPx/GPx4) and Se...
Testicular Development and Spermatogenesis: Harvesting the Postgenomics Bounty
Antoine D. Rolland, Bernard Jegou and Charles Pineau
Spermatogenesis is a sophisticated process facilitating transmission of the genetic patrimony and, thus, perpetuation of the species. Mammalian spermatogenesis is classically divided into three 3 phas...
