Chapter category:
The NOSTRIN Subfamily of PCH/F‑BAR Proteins
The Pombe Cdc15 Homology Proteins
Edited by: Pontus AspenströmISBN: TBA
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Chapter authors:
Ann Siehoff-Icking, Masood Siddique and Werner Müller-Esterl
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Ann Siehoff-Icking
Masood Siddique
Werner Müller-Esterl
Institute for Biochemistry II, Frankfurt, Germany
Additional chapters from this book:
The PACSIN Proteins and their Role in Membrane Trafficking
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PACSIN 1/syndapin 1 was originally identified by its drastic expression decrease during CNS repair processes and by virtue of its binding to the GTPase dynamin. The three family members play important...
F‑BAR Domain Proteins in Schizosaccharomyces pombe
Rachel H Roberts-Galbraith and Kathleen L. Gould
S chizosaccharomyces pombe is a simple model organism ideal for study of conserved proteins of interest. The genome of S. pombe encodes seven proteins containing F‑BAR domains, including f...
The CIP4 Family of F‑BAR Domain‑Containing Proteins
Marcia Toguchi and Pontus Aspenström
The F‑BAR family of proteins has emerged as important coordinators of signaling pathways that regulate actomyosin assembly and membrane dynamics. This review article will focus on the Cdc42̴...
The NOSTRIN Subfamily of PCH/F‑BAR Proteins
Ann Siehoff-Icking, Masood Siddique and Werner Müller-Esterl
NOSTRIN is a prototypic PCH/F‑BAR protein with an N‑terminal F‑BAR domain mediating membrane association and a C‑terminal SH3 domain representing a docking platform for various...
FES and FER: The F‑BAR Domain‑Containing Protein‑Tyrosine Kinases
Waheed Sangrar, Andrew W. Craig and Peter A. Greer
FES and FER are the only two members of a distinct subgroup of the protein‑tyrosine kinase (PTK) family. What distinguishes them from other PTKs and indeed all other kinases, are their unique am...
PSTPIP1 and PSTPIP2/MAYP
Violeta Chitu and E. Richard Stanley
PSTPIP1 and PSTPIP2 are expressed predominantly in the hematopoietic system where their C‑terminal tyrosine phosphorylation is regulated by PEST family phosphatases. Both proteins deform membran...
Boomerangs, Bananas and Blimps: Structure and Function of F‑BAR Domains in the Context of the BAR Domain Superfamily
Adam Frost, Vinzenz M. Unger and Pietro De Camilli
Proteins that belong to the BAR (Bin, Amphiphysin, RVS) domain superfamily are alpha‑helical bilayer‑binding modules that have evolved to induce or stabilize membrane curvature during cell...
The Budding Yeast PCH/F‑BAR Proteins
Alan L. Munn
The budding yeast Saccharomyces cerevisiae genome encodes two classical Pombe Cdc15 Homology (PCH) proteins: Hof1p (or Cyk2p) and Bzz1p (or Lsb7p). Like mammalian PCH proteins, both have an N‑te...
Gas7
Wenlynn B. Su, Jhong-Jhe You, Bo-Tsang Huang, Viswanathan Sivakumar, Shauh-Der Yeh and Sue Lin-Chao
Gas7 (growth‑arrest specific gene 7) has recently been classified to be a member of the Pombe Cdc 15 homology (PCH) family and belongs to the proline, serine, threonine‑rich phosphatase in...
