Angiogenesis
Chapters
« previous | page 2 of 2 pagesVEGF and Tumor Progression in Human Melanoma
Domenico Ribatti, Angelo Vacca and Franco Dammacco
Angiogenesis occurs in pathological conditions, such as tumors, where a specific critical point is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, able to stimulate the ...
VEGF in Colorectal Cancer
Markus Guba, Hendrik Seeliger, Karl-Walter Jauch and Christiane J. Bruns
Angiogenesis plays an important role in colorectal cancer progression. Evidence from preclinical and clinical studies indicates that vascular endothelial growth factor (VEGF) is the predominant angiogenic factor in human colorectal cancer and is associated with formation of metastases and poor pr...
VEGF in Esophageal Cancer
Axel Kleespies, Markus Guba, Karl-Walter Jauch and Christiane J. Bruns
Esophageal carcinoma growth is relatively fast and patients generally have a poor prognosis. The influence of angiogenesis and pro-angiogenic molecules such as vascular endothelial growth factor (VEGF) on progression and recurrence of esophageal carcinoma has been debated over the last years. In ...
VEGF in Hematopoietic Malignancy
Philip T. Murphy and John Quinn
Increasing evidence suggests that angiogenesis plays an important role in the pathogenesis of all major hematopoietic malignancies. For example, increased angiogenesis has been correlated with risk of progression in chronic lymphocytic leukemia and lymphomas and with poor prognosis in myeloma and...
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