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Surgery

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Radiological Intervention for Treatment of Complications after Liver Transplantation

Giovanni Gandini, Maria Carla Cassinis, Dorico Righi, Andrea Doriguzzi-Breatta, Maria Cristina Martina and Maria Antonella Ruffino

Orthotopic liver transplantation (OLT) is a widely accepted treatment for end‑stage chronic liver disease and severe liver failure. Despite improvement in survival due to advances in surgical technique, organ preservation technology and immunosuppressive strategies, there are significant compl...

Resection of Noncolorectal Cancer Liver Metastases

Cristina R. Ferrone and Kenneth K. Tanabe

The liver remains second only to the regional lymph nodes as the most common site of metastases from gastrointestinal tract malignancies. Other primary tumors outside of the gastrointestinal tract also metastasize to the liver, but with a lower frequency. The safety of hepatic resection has improved...

Response Evaluation Criteria in Hepatocellular Carcinoma (Moving beyond the Recist)

Carlo Fugazzola, Gianpaolo Carrafiello, Chiara Recaldini, Elena Bertolotti, Tamara Cafaro, Maria Gloria Angeretti, Paolo Nicotera and Domenico Lumia

To assess the clinical success of percutaneous minimally invasive therapies for HCC, conventional anatomical imaging based upon size criteria alone (WHO and RECIST) is not sufficient; therefore, additional criteria provided by new imaging techniques, concerning neoangiogenesis and tumor metabolism, ...

Secondary Abdominal Compartment Syndrome in Burns

Michael E. Ivy

P of developing intra-abdominal hypertension (IAH). Patients large, greater than 70% TBSA, are at risk of developing abdominal syndrome (ACS), particularly if they have a concurrent inhalation injury. IAH and ACS is related to the volume of crystalloid fluid infused during and does not require a...

Sepsis after Liver Resection: Predisposition, Clinical Relevance and Synergism with Liver Dysfunction

Gennaro Nuzzo, Ivo Giovannini, Felice Giuliante, Francesco Ardito and Carlo Chiarla

Liver resection, compared with other abdominal operations, is characterized by greater predisposition to septic complications. This may be explained by several factors, including the major role of the liver in immune defence, anatomical features such as the close relationship of the hepato‑bil...

Sequential Arterial and Portal Vein Embolization before Right Hepatectomy in Patients with Cirrhosis and Hepatocellular Carcinoma

Jacques Belghiti, Béatrice Aussilhou and Valérie Vilgrain

Major hepatectomy for large HCC in patients remains a crucial procedure due to the possibility of a low regeneration of the future liver remnant (FLR). It has been demonstrated that preoperative portal vein embolization (PVE) increase the tolerance of right hepatectomy. Selective transcatheter arter...

Staging Algorithms for Patients with HCC and Prognostic Indicators

Christos S. Georgiades

Assigning a specific prediction of survival to any patient with HCC is difficult under the best of circumstances. The nature of the disease, the underlying liver function, the performance status of the patients as well as the misleading conclusions with which the relevant literature is replete, all ...

Staging Systems to Predict Survival in Hepatocellular Carcinoma

Sonia Pascual and Miguel Pérez-Mateo

There has been a considerable controversy regarding which is the best prognostic staging system to predict survival in patients with cirrhosis and hepatocellular carcinoma (HCC). Several prognostic models have been developed in the recent years but none has been widely accepted. The staging systems ...

Surgical Strategies and Technique for Hilar Cholangiocarcinoma

Tsuyoshi Sano and Yuji Nimura

Hepatobiliary resection for hilar cholangiocarcinoma (HC) remains a technically demanding procedure, calling for a high level of expertise in biliary and hepatic surgery. Treatment strategy for HC includes preoperative staging, perioperative managements and radical surgery. Multidetector row compute...

Transection Techniques in Liver Surgery

Luigi Boni, Gianlorenzo Dionigi, Mario Diurni, and Renzo Dionigi

The main problem which is experienced during liver resection still remains the bleeding control in course of parenchymal division. Over the past decades several techniques such as crush‑clamp, ultrasonic dissection, radiofrequency or stapler assisted liver dissection have been proposed in orde...

Vascular Isolation Techniques in Liver Resection

Jacques Belghiti, Safi Dokmak and Catherine Paugam-Burtz

During liver resection, various techniques of hepatic vascular control have been proposed to minimize the intraoperative blood losses. They include the isolated occlusion of the hepatic inflow (pedicular clamping) or the combination of occlusion of the hepatic inflow and outflow (total vascular excl...

Virtual Liver Surgery: Computer-assisted operation planning in 3D liver model

Hauke Lang, Milo Hindennach, Arnold Radtke and Heinz Otto Peitgen

Ongoing development in CT imaging-based computer assistance has enabled an optimal visualization of the intrahepatic vascular branching in a virtual 3D liver model providing an individual territorial liver mapping as well as volume calculation of the corresponding vascular territories. Thus, liver r...


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